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ICD-10-CM Current in FY 2027

Z17.421

Hormone receptor negative with human epidermal growth factor receptor 2 negative status

Release
FY 2027
Effective

Hierarchy

Where Z17.421 sits in the official hierarchy. Each level is the code it is classified under.

  1. Z17 Estrogen, and other hormones and factors receptor status
  2. Z17.4 Combined receptor status
  3. Z17.42 Parent Hormone receptor negative
  4. Z17.421 This code Hormone receptor negative with human epidermal growth factor receptor 2 negative status

Official Coding Notes

Reproduced verbatim from the FY 2027 ICD-10-CM files. Notes labelled as inherited are declared on a parent code and apply here too.

Inclusion Terms

HR- with HER2-

Inclusion Terms

TNBC

Inclusion Terms

Triple negative breast cancer

Code First

malignant neoplasm, such as:

Inherited from Z17 — Estrogen, and other hormones and factors receptor status

Code First

malignant neoplasm of breast ( C50 .-)

Inherited from Z17 — Estrogen, and other hormones and factors receptor status

Code First

malignant neoplasm of ovary ( C56 .-)

Inherited from Z17 — Estrogen, and other hormones and factors receptor status

Version History

How Z17.421 appears in each release imported from the official files, newest first.

  1. FY 2027 Effective

    Current

    Hormone receptor negative with human epidermal growth factor receptor 2 negative status

  2. FY 2026 Effective

    Unchanged

    Hormone receptor negative with human epidermal growth factor receptor 2 negative status

Other codes under Z17.42

Data Source

Code information on this page is derived from the FY 2027 ICD-10-CM files published by CDC NCHS and CMS.

Release
FY 2027
Effective
Source file
icd10cm-code-descriptions-2027.zip

Official ICD-10-CM source files (opens in a new tab)

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