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ICD-10-CM Current in FY 2027

M35.81

Multisystem inflammatory syndrome

Release
FY 2027
Effective

Hierarchy

Where M35.81 sits in the official hierarchy. Each level is the code it is classified under.

  1. M35 Other systemic involvement of connective tissue
  2. M35.8 Parent Other specified systemic involvement of connective tissue
  3. M35.81 This code Multisystem inflammatory syndrome

Official Coding Notes

Reproduced verbatim from the FY 2027 ICD-10-CM files. Notes labelled as inherited are declared on a parent code and apply here too.

Inclusion Terms

MIS-A

Inclusion Terms

MIS-C

Inclusion Terms

Multisystem inflammatory syndrome in adults

Inclusion Terms

Multisystem inflammatory syndrome in children

Inclusion Terms

Pediatric inflammatory multisystem syndrome

Inclusion Terms

PIMS

Excludes1

reactive perforating collagenosis ( L87.1 )

Inherited from M35 — Other systemic involvement of connective tissue

Code First

, if applicable, COVID-19 ( U07.1 )

Use Additional Code

code, if applicable, for:

Use Additional Code

exposure to COVID-19 or SARS-CoV-2 infection ( Z20.822 )

Use Additional Code

personal history of COVID-19 ( Z86.16 )

Use Additional Code

post COVID-19 condition ( U09.9 )

Code Also

any associated complications such as:

Code Also

acute hepatic failure ( K72.0- )

Code Also

acute kidney failure ( N17 .-)

Code Also

acute myocarditis ( I40 .-)

Code Also

acute respiratory distress syndrome ( J80 )

Code Also

cardiac arrhythmia (I47-I49.-)

Code Also

pneumonia due to COVID-19 ( J12.82 )

Code Also

severe sepsis ( R65.2- )

Code Also

viral cardiomyopathy ( B33.24 )

Code Also

viral pericarditis ( B33.23 )

Version History

How M35.81 appears in each release imported from the official files, newest first.

  1. FY 2027 Effective

    Current

    Multisystem inflammatory syndrome

  2. FY 2026 Effective

    Unchanged

    Multisystem inflammatory syndrome

Other codes under M35.8

Codes whose official notes reference M35.81

Data Source

Code information on this page is derived from the FY 2027 ICD-10-CM files published by CDC NCHS and CMS.

Release
FY 2027
Effective
Source file
icd10cm-code-descriptions-2027.zip

Official ICD-10-CM source files (opens in a new tab)

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